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100Tests $ 100.00
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For research use only.

Alternate Names BIT,  CD172 antigen-like family member A,  P84,  PTPNS1,  SHPS-1,  SIRPα
Clone No
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Background CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Abbre CD172a
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG1, κ
Isotype Control E-AB-F09822C
Applications
FCM
Research Areas Cell Adhesion;Cell Biology;Immunology;Signal Transduction
Cellular Localization
Membrane
Form Liquid
Conjugation FITC
Conjugation Information FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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Elab Fluor®488

Elab Fluor®700

FITC

None (AF/LE)

Unconjugated

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