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FITC Anti-Human CD49d Antibody[9F10] (E-AB-F1144C)

AllSizePriceQty
100Tests $ 220.00
20Tests $ 90.00
100Tests×2 $ 330.00
Add to cart

For research use only.

Alternate NamesCD49 antigen-like family member D,  CD49d,  ITGA4,  Integrin alpha-4,  Integrin alpha-IV,  VLA-4 subunit alpha
Clone No
Leadtime Order now, ship in 3 days
BackgroundCD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
AbbreCD49d
Swissprot
HostMouse
ReactivityHuman
ClonalityMonoclonal
Isotype Mouse IgG1, κ
Isotype Control E-AB-F09792C
Applications
FCM
Research AreasCell Adhesion;Cell Biology;Immunology;Innate Immunity
Cellular Localization
Membrane
FormLiquid
Concentration
5 μL/Test
ConjugationFITC
Conjugation InformationFITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12 months
ShippingIce bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

1 Results

    Other Formats

    1 Results

    APC

    Elab Fluor®488

    Elab Fluor®647

    Elab Fluor®700

    FITC

    None (AF/LE)

    PE

    PE/Cyanine 5

    PE/Cyanine 5.5

    PE/Cyanine 7

    PE/Elab Fluor®594

    PerCP/Cyanine 5.5

    Unconjugated

      Product Information