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For research use only.

Alternate Names IAP,  Rh-associated protein,  gp42,  integrin-associated protein,  neurophilin
Clone No
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Background CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Abbre CD47
Swissprot
Host Mouse
Reactivity Human
Clonality Monoclonal
Isotype Mouse IgG1, κ
Isotype Control E-AB-F09792C
Applications
FCM
Research Areas Immunology;Innate Immunity
Cellular Localization
Membrane
Form Liquid
Conjugation FITC
Conjugation Information FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

Elab Fluor®700

Elab Fluor®Violet 450

FITC

None (AF/LE)

PE

PE/Cyanine 5

PE/Cyanine 5.5

PE/Cyanine 7

PE/Elab Fluor®594

PerCP

PerCP/Cyanine 5.5

Unconjugated

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