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For research use only.

Verified Samples Verified Samples in WB: Mouse skeletal muscle
Verified Samples in IHC: Human cervical cancer, Human brain
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human FHL3
Abbre FHL3
Synonyms FHL 3,  FHL-3,  FHL3,  Fhl3,  Four and a half LIM domains 3,  Four and a half LIM domains protein 3,  SLIM-2,  SLIM2,  Skeletal muscle LIM protein 2,  Skeletal muscle LIM-protein 2
Swissprot
Calculated MW 31 kDa
Cellular Localization Cytoskeleton, stress fiber, Nucleus, Other locations: focal adhesion, Z disc.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
Other Clones

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Unconjugated

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