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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human FBXO45
Abbre FBXO45
Synonyms F box protein 45,  F-box only protein 45,  F-box/SPRY domain-containing protein 1,  FBSP1,  FBX45,  fbxo45,  hFbxo45
Swissprot
Cellular Localization Cell junction>synapse>postsynaptic cell membrane. Cell junction>synapse>presynaptic cell membrane.
Concentration 1.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cell Biology,  Epigenetics and Nuclear Signaling,  Developmental biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).
Other Clones

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Unconjugated

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