EZR Polyclonal Antibody (E-AB-15004)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse kidney Verified Samples in IHC: Human thyroid cancer, Human esophagus cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human EZR |
| Abbre | EZR |
| Synonyms | CVIL, CVL, Cytovillin, Cytovillin 2, DKFZp762H157, EZR, EZRI, Epididymis secretory protein Li 105, Ezrin, FLJ26216, HEL S 105, MGC1584, VIL 2, VIL2, Villin 2, Villin 2 (ezrin), Villin 2 ezrin, Villin-2, Villin2, p81 |
| Swissprot | |
| Calculated MW | 69 kDa |
| Cellular Localization | Apical cell membrane. Cell projection. Cell projection>microvillus membrane. Cell projection>ruffle membrane. Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
Other Clones
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Other Formats
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Unconjugated
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