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For research use only.

Verified Samples Verified Samples in IHC: Human gastric cancer, Human thyroid cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human ESPL1
Abbre ESPL1
Synonyms Caspase like protein ESPL1,  Caspase-like protein ESPL1,  ESP 1,  ESP1,  ESPL 1,  ESPL1,  Espl1,  Extra spindle poles like 1,  Extra spindle poles like 1 protein,  Extra spindle poles-like 1 protein,  FLJ46492,  KIAA0165,  S,  Separase,  Separin,  Similar to fission yeast cut1and gene
Swissprot
Cellular Localization Cytoplasm. Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell biology,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Other Clones

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Unconjugated

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