ERK 1 Monoclonal Antibody (E-AB-22246)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human breast carcinoma |
| Dilution | IHC 1:100-200 |
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC-p |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein of ERK1 of MAPK3 |
| Abbre | ERK1 Mouse (1C11) |
| Synonyms | ERK, ERK 1, ERK-1, ERK1, ERT 2, ERT2, Extracellular Signal Regulated Kinase 1, Extracellular signal related kinase 1, Extracellular signal-regulated kinase 1, HGNC6877, HS44KDAP, HUMKER1A, Insulin Stimulated MAP2 Kinase, Insulin-stimulated MAP2 kinase, MAP, MAP kinase 1 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, Cytosol, Endosome, early endosome, late endosome, Extracellular region or secreted, extracellular exosome, Golgi apparatus, Golgi apparatus, Mitochondrion, Nucleus, nuclear envelope, nucleoplasm, nucleus, Plasma Membrane, caveola, plasma membrane, Other locations: cytoplasm, focal adhesion, protein complex, pseudopodium. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Clone No. | 1C11 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4). |
Other Clones
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Other Formats
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Unconjugated
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