EPS15 Polyclonal Antibody (E-AB-17923)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human colorectal cancer |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human EPS15 |
| Abbre | EPS15 |
| Synonyms | AF 1P, AF 1p protein, AF1P, ALL1 fused gene from chromosome 1, EPS 15, Epidermal growth factor receptor pathway substrate 15, Epidermal growth factor receptor substrate 15, MLLT 5, MLLT5, Protein Eps 15, Protein Eps15 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cell membrane, Peripheral membrane protein, Cytoplasmic side, Recruited to the plasma membrane upon EGFR activation and localizes to coated pits. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15) is a Protein Coding gene. Diseases associated with EPS15 include Vaccinia. Among its related pathways are Notch signaling pathway (KEGG) and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and SH3 domain binding. An important paralog of this gene is EPS15L1. |
Other Clones
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Other Formats
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Unconjugated
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