ENPP2 Polyclonal Antibody (E-AB-19626)

For research use only.
Verified Samples |
Verified Samples in IHC: Human liver cancer, Human brain |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human ENPP2 |
Abbre | ENPP2 |
Synonyms | ATX, ATX X, Autotaxin, Autotaxin t, E NPP 2, E-NPP 2, ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase 2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Enpp2, Extracellular lysophospholipase D, FLJ26803, LysoPLD, NPP2, PD IALPHA, PDNP2, Phospho |
Swissprot | |
Cellular Localization | Secreted. Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells. |
Concentration | 0.8 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. |
Other Clones
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Other Formats
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Unconjugated
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