Endoglin/CD105 Monoclonal Antibody (AN200002P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human renal carcinoma, Human tonsil, Human liver |
| Dilution | IHC-P 1:200-1:2000, |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human Endoglin / CD105 Protein |
| Abbre | ENG |
| Synonyms | HHT, RP11 228B, Osler Rendu Weber syndrome, END, HHT1, ORW1, CD105, ENG, endoglin, AI528660, AI662476, CD 105, CD105 antigen, EGLN, FLJ41744, ORW, Osler Rendu Weber syndrome 1, RP11 228B15.2, S-endoglin, SN6, AI528660, AI662476, CD 105, CD105, CD105 antigen, EGLN, END, Endoglin, Eng, FLJ41744, HHT1, ORW, ORW1, Osler Rendu Weber syndrome 1, RP11 228B15.2, S-endoglin, SN6, ENG, END |
| Swissprot | |
| Cellular Localization | Cell membrane |
| Tissue Specificity | Detected on umbilical veil endothelial cells, Detected in placenta (at protein level), Detected on endothelial cells. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Immunology, Stem Cells, Cancer, Cardiovascular |
| Clone No. | 3P6 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins (1-3). Endoglin and Betaglycan/T beta RIII are type III receptors for TGF beta superfamily ligands, sharing 71% aa identity in the transmembrane (TM) and cytoplasmic domains. Endoglin is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta, with lower amounts on hematopoietic, mesenchymal and neural crest stem cells, activated monocytes, and lymphoid and myeloid leukemic cells. |
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Unconjugated
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