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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer
Dilution IHC 1:40-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human ENAH
AbbreENAH
Synonyms Actin Regulator,  ENAH,  Enabled Homolog (Drosophila),  MENA,  Mammalian Enabled Variant 11a,  Mammalian Enabled Variant Pan,  Protein Enabled Homolog.
Swissprot
Cellular LocalizationCytoplasm. Cytoplasm>cytoskeleton. Cell projection>lamellipodium. Cell projection>filopodium. Cell junction>synapse. Cell junction>focal adhesion. Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with a number of other proteins including vinculin and zyxlin. Colocalizes with N-WASP at the leading edge. Colocalizes with GPHN and PFN at synapses.
Concentration1.8 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAntigen affinity purification
Research AreasCancer,  Cell Biology,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThis gene encodes a member of the enabled/ vasodilator-stimulated phosphoprotein. Members of this gene family are involved in actin-based motility. This protein is involved in regulating the assembly of actin filaments and modulates cell adhesion and motility. Alternate splice variants of this gene have been correlated with tumor invasiveness in certain tissues and these variants may serve as prognostic markers. A pseudogene of this gene is found on chromosome 3.ENAH (Enabled Homolog (Drosophila)) is a Protein Coding gene. Among its related pathways are TCR signaling (REACTOME) and Innate Immune System. GO annotations related to this gene include actin binding and WW domain binding. An important paralog of this gene is EVL.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated