Elab Fluor® 647 Anti-Human/Mouse Integrin β7 Antibody[FIB21] (AN00423M)
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For research use only.
Alternate Names | β7 Integrin, integrin βp, ITGB7 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin. |
Abbre | Integrin β7 |
Swissprot | |
Host | Rat |
Reactivity | Human;Mouse |
Clonality | Monoclonal |
Isotype | Rat IgG2b, κ |
Isotype Control | E-AB-F09842M |
Applications | FCM |
Cellular Localization | Membrane |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | Elab Fluor®647 |
Conjugation Information | Elab Fluor® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Elab Fluor®647
PE
PE/Elab Fluor®594
PerCP/Cyanine 5.5
