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Elab Fluor® 488 Anti-Human CD192/CCR2 Antibody[K036C2] (E-AB-F1385L)

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AllSizePriceQty
100Tests $ 260.00
20Tests $ 100.00
100Tests×2 $ 390.00
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For research use only.

Alternate NamesCC-CKR-2,  CCR2A,  CCR2B,  CKR2,  CKR2A,  CKR2B,  CMKBR2,  MCP-1-R
Clone No
Leadtime Order now, ship in 3 days
BackgroundCCR2 is a chemokine receptor that binds monocyte chemoattractant proteins (MCP-1, 2, 3 and 4). Two spliced variants were initially described for CCR2 (CCR2A and CCR2B). These variants differ in their terminal carboxyl tails. Monocyte adhesion to the arterial endothelium and subsequent migration into the intima are central events in the pathogenesis of atherosclerosis. CCR2 and MCP-1 have been associated to atherosclerotic plaques. MCP-1 is induced by modified-LDL in endothelial cells and may trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Local overexpression of MCP-1 at vessel walls induces infiltration of macrophages and formation of atherosclerotic lesions. Obesity induces an inflammatory state that is implicated in many clinically important complications, including insulin resistance, diabetes, atherosclerosis, and non-alcoholic fatty liver disease. CCR2 influences the development of obesity and associated adipose tissue inflammation.
AbbreCD192
Swissprot
HostMouse
ReactivityHuman
ClonalityMonoclonal
Isotype Mouse IgG2a, κ
Isotype Control E-AB-F09802L
Applications
FCM
Research AreasCell Adhesion;Cell Biology;Immunology;Innate Immunity;Neuroinflammation;Neuroscience
Cellular Localization
Membrane
FormLiquid
ConjugationElab Fluor®488
Conjugation InformationElab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12 months
ShippingIce bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

1 Results

    Other Formats

    1 Results

    APC

    Elab Fluor®488

    PE

    PerCP/Cyanine 5.5

    Unconjugated

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