EIF4EBP1 Polyclonal Antibody (E-AB-66892)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colon carcinoma |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | A synthetic peptide of human EIF4EBP1 |
Abbre | EIF4EBP1 |
Synonyms | 4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I |
Swissprot | |
Calculated MW | 12 kDa |
Cellular Localization | cytoplasm, cytosol. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
Other Clones
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Other Formats
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Unconjugated
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