EGLN1 Polyclonal Antibody (E-AB-65402)

For research use only.
Verified Samples |
Verified Samples in IF: MCF-7 |
Dilution | IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human EGLN1 (NP_071334.1). |
Abbre | EGLN1 |
Synonyms | C1orf12, ECYT3, EGLN1, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 |
Swissprot | |
Cellular Localization | Cytosol, Nucleus, Other locations: cytoplasm. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). |
Other Clones
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Other Formats
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Unconjugated
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