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EFNB1 Polyclonal Antibody (E-AB-53525)

AllSizePriceQty
200μL $ 399.00
120μL $ 240.00
60μL $ 143.00
20μL $ 73.00
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For research use only.

Verified Samples Verified Samples in IHC: Human brain
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human EFNB1
AbbreEFNB1
SynonymsCFND,  CFNS,  Craniofrontonasal syndrome (craniofrontonasal dysplasia),  EFL 3,  EFL-3,  EFL3,  EFNB1,  ELK ligand,  ELK-L,  EPH-related receptor tyrosine kinase ligand 2,  EPLG2,  Elk L,  Eph related receptor tyrosine kinase ligand 2,  Ephrin-B1,  LERK 2,  LERK-2,  LERK2,  Ligand o
Swissprot
Cellular LocalizationMembrane.
Concentration0.9 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAntigen affinity purification
Research AreasCell Biology,  Cardiovascular,  Developmental Biology,  Neuroscience,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundEphrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated