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For research use only.
Verified Samples | Verified Samples in IHC: Human brain |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human EFNB1 |
Abbre | EFNB1 |
Synonyms | CFND, CFNS, Craniofrontonasal syndrome (craniofrontonasal dysplasia), EFL 3, EFL-3, EFL3, EFNB1, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, Elk L, Eph related receptor tyrosine kinase ligand 2, Ephrin-B1, LERK 2, LERK-2, LERK2, Ligand o |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 0.9 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cell Biology, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. |
Other Clones
1 Results
Other Formats
1 Results
Unconjugated