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100μL $ 320.00
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For research use only.

Verified Samples Verified Samples in IF: HCT116
Dilution ICC/IF 1:20-1:100,  
Isotype IgG1
Host Mouse
Reactivity Human
Applications ICC/IF
Clonality Monoclonal
Immunogen Recombinant Human DR5/TRAIL R2 Protein
Abbre TNFRSF10B
Synonyms UNQ,  PRO,  Death Receptor,  TRAIL Receptor,  TNF-Related Apoptosis-Inducing Ligand Receptor,  TRICK,  ZTNFR,  TRAILR,  TRAIL-R,  KILLER/DR,  CD262,  DR5,  KILLER,  KILLER/DR5,  TRAIL-R2,  TRAILR2,  TRICK2,  TRICK2A,  TRICK2B,  TRICKB,  ZTNFR9,  TNFRSF10B,  Death Receptor 5,  TNF-Related Apoptosis-Inducing Ligand Receptor 2,  TRAIL Receptor 2,  Tumor Necrosis Factor Receptor Superfamily Member 10B,  UNQ160,  PRO186,  DR5,  KILLER,  TNFRSF10b
Swissprot
Cellular Localization Membrane
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Cell Biology,  Signal Transduction,  Cancer,  Cardiovascular
Clone No. 11G5
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
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Unconjugated

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