DNAJC2 Polyclonal Antibody (E-AB-17815)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colorectal cancer, Human ovarian cancer |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human DNAJC2 |
Abbre | DNAJC2 |
Synonyms | AU020218, DNJC2, DnaJ (Hsp40) homolog subfamily C member 2, DnaJ homolog subfamily C member 2, Dnajc2, M phase phosphoprotein 11, M-phase phosphoprotein 11, MGC105894, MIDA1, MPHOSPH11, MPP11, OTTMUSP00000031226, ZRF1, ZUO1, Zrf2, Zuotin related , Zuotin related factor 1 |
Swissprot | |
Cellular Localization | Nucleus. Cytoplasm>cytosol. |
Concentration | 1.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Signal Transduction, Cancer |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene is a member of the M-phase phosphoprotein (MPP) family.The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol.The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome.This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts.Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors.This gene has a pseudogene on chromosome 6.Alternatively spliced variants which encode different protein isoforms have been described. |
Other Clones
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Other Formats
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Unconjugated
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