CYP17A1 Polyclonal Antibody (E-AB-11124)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human gastric cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CYP17A1 |
| Abbre | CYP17A1 |
| Synonyms | 20 lyase, CP17A, CPT7, CYP17, CYP17A1, CYPXVII, Cytochrom, Cytochrome P450 17A1, Cytochrome P450 family 17, Cytochrome P450 family 17 subfamily A polypeptide 1, Cytochrome p450 XVIIA1, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. |
Other Clones
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Other Formats
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Unconjugated
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