CXCL9/MIG Polyclonal Antibody(Capture/Detector) (AN003890P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human CXCL9/MIG protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | ELISA Capture/Detector |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human CXCL9/MIG Protein expressed by E.coli |
| Abbre | CXCL9/MIG |
| Synonyms | crg, CXCL, SCYB, C-X-C Motif Chemokine, Small-Inducible Cytokine B, Chemokine(C-X-C motif) ligand, CXCL9, CMK, Humig, MIG, SCYB9, crg-10, Chemokine(C-X-C motif) ligand 9, C-X-C Motif Chemokine 9, Gamma-Interferon-Induced Monokine, Monokine induced by gamma interferon, Monokine Induced by Interferon-Gamma, Monokine Induced by Interferon-γ, Small-Inducible Cytokine B9 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | C-X-C motif chemokine ligand 9 (CXCL9, MIG) is a soluble chemokine expressed by multiple cell types, such as endothelial cells, monocytes, and tumor cells. The expression of CXCL9 is upregulated in response to proinflammatory cytokines, such as IFN-γ and TNF-α. (1,2). CXCL9 binds to CXCR3, a GPCR that is expressed on the surface of multiple populations of immune cells, particularly exclusively activated T lymphocytes (3). Binding of CXCL9 to CXCR3 promotes T cell chemotaxis and infiltration into sites of inflammation that form in settings such as viral infection and tumorigenesis (4-6). Research studies have demonstrated production of CXCL9 by tumor cells mediates tumor suppression through the recruitment of tumor antigen-specific T cells (7). |
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