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For research use only.

Verified Samples Verified Samples in WB: 293T
Verified Samples in IHC: Human thyroid cancer, Human colon cancer
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CUL3
Abbre CUL3
Synonyms CUL 3,  CUL3,  Cul-3,  Cullin-3,  Cullin3,  KIAA0617,  PHA2E,  cul3
Swissprot
Calculated MW 89 kDa
Cellular Localization Nucleus. Golgi apparatus.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Other Clones

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Unconjugated

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