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For research use only.

Verified Samples Verified Samples in IF: HeLa
Dilution IF 1:10-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human CUL1 (NP_003583.2).
Abbre CUL1
Synonyms CUL1,  Cullin 1,  MGC149834,  MGC149835,  cullin-1
Swissprot
Cellular Localization Cytosol, Nucleus, nucleoplasm, Other locations: cullin-RING ubiquitin ligase complex, Parkin-FBXW7-Cul1 ubiquitin ligase complex, SCF ubiquitin ligase complex.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background CUL1 (Cullin 1) is a Protein Coding gene. Diseases associated with CUL1 include Vaccinia and Weaver Syndrome. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and FBXW7 Mutants and NOTCH1 in Cancer. Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding. An important paralog of this gene is CUL2.
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Unconjugated

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