CRISP3 Polyclonal Antibody (E-AB-11104)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human colon cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CRISP3 |
| Abbre | CRISP3 |
| Synonyms | Aeg 2, Aeg2, CRIS3, CRISP 3, CRISP-3, CRS 3, CRS3, Crisp3, Cysteine rich secretory protein 3, Cysteine-rich secretory protein 3, MGC126588, OTTHUMP00000016590, OTTHUMP00000039911, SGP 28, SGP28, SGP28 protein, Specific granule , Specific granule protein (28 kDa), dJ442L6.3 |
| Swissprot | |
| Cellular Localization | Secreted. In neutrophils, localized in specific granules. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. |
Other Clones
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Other Formats
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Unconjugated
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