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For research use only.

Verified Samples Verified Samples in IHC: Human kidney, Mouse liver, Mouse kidney
Dilution IHC 1:300-1:1000
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse Endostatin
Abbre COL18A1
Synonyms Antiangiogenic agent,  COIA1,  Col18a1,  Collagen alpha 1(XVIII) chain,  Collagen type XVIII alpha 1,  Endostatin,  KNO,  KNO1,  KS,  Multi functional protein MFP
Swissprot
Cellular Localization Secreted, extracellular space, extracellular matrix.
Concentration 1.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes the alpha chain of type XVIII collagen.This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains.The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein.Mutations in this gene are associated with Knobloch syndrome.The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Clones

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Unconjugated

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