CNPY3 Polyclonal Antibody (E-AB-52728)
For research use only.
| Verified Samples |
Verified Samples in WB: OP9, HepG2, NIH/3T3 Verified Samples in IHC: Human cervical cancer, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CNPY3 |
| Abbre | CNPY3 |
| Synonyms | CAG repeat containing, CAG4A, CNPY3, CTG repeat protein 4a, Canopy 3 homolog, ERDA 5, ERDA5, Expanded repeat domain CAG/CTG 5, Expanded repeat-domain protein CAG/CTG 5, OTTHUMP00000016408, PRAT4A, Protein associated with Tlr4, Protein associated with Toll like , cnpy3 |
| Swissprot | |
| Calculated MW | 31 kDa |
| Observed MW |
Refer to figures
The actual band is not consistent with the expectation.
Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Cellular Localization | Endoplasmic reticulum. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | CNPY3 (Canopy FGF Signaling Regulator 3) is a Protein Coding gene. Diseases associated with CNPY3 include Swayback. Among its related pathways are Innate Immune System and Activated TLR4 signalling. GO annotations related to this gene include receptor binding. An important paralog of this gene is CNPY4.This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. |
Other Clones
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Other Formats
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Unconjugated
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