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For research use only.

Verified Samples Verified Samples in WB: Human testis
Verified Samples in IHC: Human tonsil, Human breast cancer
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CLIC1
Abbre CLIC1
Synonyms CLIC 1,  CLIC1,  Chloride channel ABP,  Chloride intracellular channel 1,  Chloride intracellular channel protein 1,  G6,  NCC 27,  NCC27,  Nuclear chloride ion channel 27,  Nuclear chloride ion channel protein,  Regulatory nuclear chloride ion channel pr,  hRNCC,  p64CLCP
Swissprot
Calculated MW 27 kDa
Cellular Localization Nucleus. Nucleus membrane. Cytoplasm. Cell membrane. Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Other Clones

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Unconjugated

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