CITED4 Polyclonal Antibody (E-AB-19707)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CITED4 |
| Abbre | CITED4 |
| Synonyms | 4, with glu/asp rich carboxy terminal domain, AU019445, AW742964, CITE4, Cbp/p300 interacting transactivator 4, Cbp/p300-interacting transactivator 4, Cited4, MRG 2, MRG-2, MSG1 related protein 2, MSG1-related protein 2, Mrg2, Tra, cbp/p300 interacting transactivator |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription.This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2.Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. |
Other Clones
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Other Formats
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Unconjugated
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