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For research use only.

Verified Samples Verified Samples in IHC: Rat liver, Human oophoroma, Mouse liver
Verified Samples in IF: C6, L929, U-2OS
Dilution IHC 1:100-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human CHD4 (NP_001264.2).
Abbre CHD4
Synonyms CHD-4,  CHD4,  Mi-2b,  Mi2-BETA,  SIHIWES
Swissprot
Cellular Localization Nucleus. Cytoplasm>cytoskeleton>centrosome. Associates with centrosomes in interphase.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Clones

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Unconjugated

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