CDC23 Polyclonal Antibody (E-AB-65204)
For research use only.
| Verified Samples |
Verified Samples in IHC: Rat spleen, Human tonsil, Mouse lung |
| Dilution | IHC 1:100-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide of human CDC23 (NP_004652.2). |
| Abbre | CDC23 |
| Synonyms | ANAPC8, APC8, CDC23, CUT23 |
| Swissprot | |
| Cellular Localization | Cytosol, Nucleus, anaphase-promoting complex, nucleoplasm, Other locations: intracellular. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
Other Clones
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Other Formats
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Unconjugated
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