CDC23 Polyclonal Antibody (E-AB-15982)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CDC23 |
| Abbre | CDC23 |
| Synonyms | ANAPC8, APC8, Anaphase promoting complex subunit 8, Anaphase-promoting complex subunit 8, Apc 8, CDC23, Cdc 23, Cell division cycle 23 homolog, Cell division cycle protein 23, Cell division cycle protein 23 homolog, Cut23, Cyclosome subu, cell division cycle 23 |
| Swissprot | |
| Cellular Localization | Cytosol, Nucleus, anaphase-promoting complex, nucleoplasm, Other locations: intracellular. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
Other Clones
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Other Formats
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Unconjugated
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