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CD63/Tspan-30/Tetraspanin-30 Monoclonal Antibody (AN200007P)

All Size Price Qty
100μL $ 320.00
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For research use only.

Verified Samples Verified Samples in IF: MCF7
Verified Samples in FCM: MCF-7
Dilution ICC/IF 1:20-1:100,  FCM 1:25-1:100,  
Isotype IgG1
Host Mouse
Reactivity Human
Applications FCM,  ICC/IF
Clonality Monoclonal
Immunogen Recombinant Human CD63 / Tspan-30 / Tetraspanin-30 protein
Abbre CD63
Synonyms MLA,  LAMP,  Tetraspanin,  CD antigen CD,  Melanoma-associated antigen ME,  Lysosomal-associated membrane protein,  CD63,  LAMP-3,  ME491,  MLA1,  OMA81H,  TSPAN30,  CD63 antigen,  CD antigen CD63,  CD63 molecule,  Granulophysin,  Lysosomal-associated membrane protein 3,  Melanoma-associated antigen ME491,  Ocular melanoma-associated antigen,  Tetraspanin-30,  Tspan-30,  LIMP,  MLA1,  LAMP-3,  CD 63,  CD63 antigen (melanoma 1 antigen),  CD63 antigen melanoma 1 antigen,  gp55,  LAMP 3,  LAMP3,  Lysosomal associated membrane protein 3,  Lysosome associated membrane glycoprotein 3,  Mast cell antigen AD1,  Melanoma 1 antigen,  Melanoma associated antigen ME491,  Melanoma associated antigen MLA1,  MGC72893,  MLA 1,  NGA,  Ocular melanoma associated antigen,  PTLGP40,  Tetraspanin 30,  Tspan 30
Swissprot
Cellular Localization Cell membrane, Lysosome membrane, Late endosome membrane, Secreted, Cell surface.
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Cardiovascular,  Immunology,  Tags & Cell Markers,  Cancer
Clone No. 5A8
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
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Unconjugated

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