CD63 Monoclonal Antibody (AN200006P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human malignant melanoma, Human lung |
| Dilution | IHC-P 1:50-1:200, |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD63 protein |
| Abbre | CD63 |
| Synonyms | MLA, LAMP, Tetraspanin, CD antigen CD, Melanoma-associated antigen ME, Lysosomal-associated membrane protein, CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30, CD63 antigen, CD antigen CD63, CD63 molecule, Granulophysin, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-30, LIMP, MLA1, LAMP-3, CD 63, CD63 antigen (melanoma 1 antigen), CD63 antigen melanoma 1 antigen, gp55, LAMP 3, LAMP3, Lysosomal associated membrane protein 3, Lysosome associated membrane glycoprotein 3, Mast cell antigen AD1, Melanoma 1 antigen, Melanoma associated antigen ME491, Melanoma associated antigen MLA1, MGC72893, MLA 1, NGA, Ocular melanoma associated antigen, PTLGP40, Tetraspanin 30, Tspan 30 |
| Swissprot | |
| Cellular Localization | Cell membraneCell membrane, Lysosome membrane, Late endosome membrane, Late endosome membrane, Late endosome membrane, Secreted, Cell surface. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Cardiovascular, Immunology, Tags & Cell Markers, Cancer |
| Clone No. | 5A7 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. |
Other Clones
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Other Formats
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Unconjugated
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