CD45/PTPRC Monoclonal Antibody (AN200165P)
For research use only.
| Verified Samples |
Verified Samples in IF: jurkat Verified Samples in FCM: Human whole blood lymphocytes |
| Dilution | ICC/IF 1:20-1:100, FCM 1:25-1:100 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM, ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD45 protein |
| Abbre | PTPRC |
| Synonyms | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, PTPRC, CD45 antigen, CD45R0, Ly-5, protein tyrosine phosphatase, receptor type, Receptor-type tyrosine-protein phosphatase C, CD45RO, Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA), T200, c polypeptide, CD 45, homolog of, Leukocyte common antigen, loc, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, receptor type C, T200 glycoprotein, T200 leukocyte common antigen, B220, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, Ly-5, LY5, Protein tyrosine phosphatase, receptor type, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Swissprot | |
| Tissue Specificity | Isoform 1: Detected in thymocytes. Isoform 2: Detected in thymocytes. Isoform 3: Detected in thymocytes. Isoform 4: Not detected in thymocytes. Isoform 5: Detected in thymocytes. Isoform 6: Not detected in thymocytes. Isoform 7: Detected in thymocytes. Isoform 8: Not detected in thymocytes. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Immunology, Signal Transduction, Neuroscience, Stem Cells, Cardiovascular |
| Clone No. | 5A6 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | CD45, previously called LCA (leukocyte common antigen), T200, or Ly5 in mice, is member C of the class 1 (receptor‑like) protein tyrosine phosphatase family (PTPRC). It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin . Multiple splicing isoforms of exon 4 (A), 5 (B), and 6 (C) are expressed according to cell type, developmental stage and antigenic exposure . The longest form, CD45RABC (called B220 in mouse) is expressed on B lymphocytes, The shortest form, CD45R0, lacking exons 4, 5 and 6 which encode aa 34‑194, is expressed on memory cells, while intermediate sizes are expressed on other T cells. |
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Other Formats
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Unconjugated
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