CD45 Polyclonal Antibody (E-AB-70024)

For research use only.
Verified Samples |
Verified Samples in IHC: Mouse liver, Mouse inflammatory spleen, Mouse lungs |
Dilution | IHC 1:500-1:1500 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD45 |
Abbre | CD45 |
Synonyms | B220, CD 45, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, LY5, Leukocyte common antigen, Ly-5, Ly5, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyros, Protein tyrosine phosphatase receptor type c polypeptide, homolog of, loc |
Swissprot | |
Cellular Localization | Cell membrane, Membrane. |
Concentration | 1.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Immunology, Neuroscience, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | CD45,also known as leukocyte common antigen (LCA),B220,and T200,is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells,except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth,differentiation,cell cycle,and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. Along with the positive selection markers (such as CD29,CD44,CD90,CD105 and CD166),negative selection markers (such as CD34 and CD45) are used for MSC identification. |
Other Clones
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Other Formats
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Unconjugated
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