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For research use only.

Verified Samples Verified Samples in IHC: Mouse spleen, Rat spleen
Dilution IHC 1:200-1:800
Isotype IgG
Host Mouse
Reactivity Mouse,  Rat
Applications IHC
Clonality Monoclonal
Immunogen Recombinant protein corresponding to Mouse TLR4
Abbre CD284
Synonyms ARMD10,  CD284,  CD284 antigen,  Homolog of Drosophila toll,  TLR 4,  TLR4,  TOLL,  Toll like receptor 4,  Toll-like receptor 4,  hToll
Swissprot
Concentration 1.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Microbiology
Clone No. 2E12C8
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Other Clones

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Unconjugated

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