CCR5 Polyclonal Antibody (E-AB-70361)

For research use only.
Verified Samples |
Verified Samples in IHC: Mouse spleen, Rat spleen, Rat thymus |
Dilution | IHC 1:200-1:800 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CCR5 |
Abbre | CCR5 |
Synonyms | AM4 7, C C CKR 5, C C chemokine receptor type 5, C-C CKR-5, C-C chemokine receptor type 5, C-C motif chemokine receptor 5 A159A, CC CKR 5, CC Chemokine Receptor 5, CC Chemokine Receptor Type 5, CC-CKR-5, CCCKR 5, CCCKR5, CCR 5, CCR-5, CCR5, CCR5 chemokine (C C motif) re |
Swissprot | |
Cellular Localization | Cell membrane. |
Concentration | 0.55 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Immunology, Microbiology, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. |
Other Clones
{{antibodyDetailsPage.numTotal}} Results
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.:{{item.cat}}
{{index}} {{goods_show_value}}
Other Formats
{{formatDetailsPage.numTotal}} Results
Unconjugated
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.:{{item.cat}}
{{index}} {{goods_show_value}}
-
IF:{{item.impact}}
Journal:{{item.journal}} ({{item.year}})
DOI:{{item.doi}}Reactivity:{{item.species}}
Sample Type:{{item.organization}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}