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For research use only.

Verified Samples Verified Samples in IHC: Mouse spleen, Rat spleen, Rat thymus
Dilution IHC 1:200-1:800
Isotype IgG
Host Rabbit
Reactivity Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse CCR5
Abbre CCR5
Synonyms AM4 7,  C C CKR 5,  C C chemokine receptor type 5,  C-C CKR-5,  C-C chemokine receptor type 5,  C-C motif chemokine receptor 5 A159A,  CC CKR 5,  CC Chemokine Receptor 5,  CC Chemokine Receptor Type 5,  CC-CKR-5,  CCCKR 5,  CCCKR5,  CCR 5,  CCR-5,  CCR5,  CCR5 chemokine (C C motif) re
Swissprot
Cellular Localization Cell membrane.
Concentration 0.55 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Microbiology,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
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Unconjugated

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