CBS Polyclonal Antibody (E-AB-14671)

For research use only.
Verified Samples |
Verified Samples in WB: Mouse pancreas, Human fetal liver |
Dilution | WB 1:200-1:1000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CBS |
Abbre | CBS |
Synonyms | AI047524, AI303044, Beta thionase, Beta-thionase, CBS, Cbs, Cbs cystathionine beta-synthase, Cystathionine beta synthase, Cystathionine beta-synthase, EC 4.2.1.22, HIP 4, HIP4, MGC18856, MGC18895, MGC37300, Methylcysteine synthase, OTTHUMP00000109416, OTTHUMP00000109418, S |
Swissprot | |
Calculated MW | 61 kDa |
Cellular Localization | Cytoplasm. Nucleus. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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