Carbonic Anhydrase XII/CA12 Monoclonal Antibody (AN200181P)
For research use only.
| Verified Samples | Verified Samples in IF: MCF7 |
| Dilution | ICC/IF 1:20-1:100 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human Carbonic Anhydrase XII/CA12 protein |
| Abbre | CA12 |
| Synonyms | CA12, CA-XII, CAXII, HsT18816, T18816, FLJ20151 |
| Swissprot | |
| Tissue Specificity | Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| Purification Method | Protein A |
| Research Areas | Cancer |
| Clone No. | 6A2 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. |
Other Clones
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Unconjugated
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