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For research use only.
| Background | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor ( TNF ) superfamily. This cytokine is mainly secreted by macrophages. It can bind to , and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation , differentiation , apoptosis , lipid metabolism , and coagulation. This cytokine has been implicated in a variety of diseases , including autoimmune diseases , insulin resistance , and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Synonyms | DIF, TNF-alpha, TNFA, TNFSF2 |
| Swissprot | |
| Reactivity | Canine |
| Specificity | Detects Canine TNF-α in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
Other Clones
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Other Formats
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Biotin
