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CAB39 Polyclonal Antibody (E-AB-16615)

AllSizePriceQty
200μL $ 399.00
120μL $ 240.00
60μL $ 143.00
20μL $ 73.00
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For research use only.

Verified Samples Verified Samples in WB: LoVo
Verified Samples in IHC: Human brain, Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human CAB39
AbbreCAB39
SynonymsCAB39,  CGI 66,  CGI-66,  CGI66,  Cab39,  Calcium binding protein 39,  Calcium-binding protein 39,  MO25,  MO25 alpha,  Mouse protein 25 alpha,  Protein Mo25
Swissprot
Calculated MW40 kDa
Cellular LocalizationCytoplasm.
Concentration0.7 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Metabolism,  Signal transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundPeutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated

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