CA4 Polyclonal Antibody (E-AB-10206)
For research use only.
| Verified Samples |
Verified Samples in WB: Human lung Verified Samples in IHC: Human colon cancer, Human prostate cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CA4 |
| Abbre | CA4 |
| Synonyms | CA IV, CA4, CAH4, CAIV, Car4, Carbonate dehydratase IV, Carbonic anhydrase 4, Carbonic dehydratase, Carbonic dehydratase IV, EC 4.2.1.1, RP17, Retinitis pigmentosa 17 (autosomal dominant) |
| Swissprot | |
| Calculated MW | 35 kDa |
| Cellular Localization | Endoplasmic reticulum, rough endoplasmic reticulum, Extracellular region or secreted, extracellular exosome, Golgi apparatus, Golgi apparatus, trans-Golgi network, Plasma Membrane, anchored component of external side of plasma membrane, apical plasma membrane, brush border membrane, plasma membrane, Other locations: cell surface, endoplasmic reticulum-Golgi intermediate compartment, membrane, perinuclear region of cytoplasm, secretory granule membrane, transport vesicle membrane. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. |
Other Clones
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Other Formats
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Unconjugated
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