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For research use only.

Verified Samples Verified Samples in IHC: Human lung cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human CSF1R
Abbre c-Fms
Synonyms C FMS,  CD 115,  CD115,  CD115 antigen,  CFMS,  CSF 1 R,  CSF 1R,  CSF-1 receptor,  CSF-1-R,  CSF1 R,  CSF1R,  CSFR,  Colony stimulating factor 1 receptor,  Colony stimulating factor I receptor,  EC 2.7.10.1,  FIM 2,  FIM2,  FMS,  FMS proto oncogene,  FMS protooncogene,  HDLS,  M-CSF Recept
Swissprot
Cellular Localization Membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
Other Clones

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Unconjugated

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