BRAF Polyclonal Antibody (E-AB-70237)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse kidney, Mouse testis, Rat brain |
| Dilution | IHC 1:200-1:800 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse B-Ra |
| Abbre | BRAF |
| Synonyms | 94 kDa B raf protein, B RAF1, B Raf proto oncogene, B Raf proto oncogene serine threonine protein kinase, B raf 1, B-Raf proto-oncogene serine/threonine-protein kinase (p94), BRAF, BRAF 1, BRAF1, FLJ95109, MGC126806, MGC138284, Muri, cRmil, serine/threonine kinase |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Cell membrane. Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. |
| Concentration | 0.74 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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