Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1]

All	Size	Price	Qty
	100μg	$ 140.00
	25μg	$ 50.00

Alternate Names	CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, Interleukin-17A
Clone No	TC11-18H10.1
Leadtime	Order now, ship in 3 days
Background	IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Abbre	IL-17A
Swissprot	Q62386
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype	Rat IgG1, κ
Isotype Control	E-AB-F09823B
Applications	ICFCM
Research Areas	Cell Biology;Immunology;Neuroinflammation;Neuroscience
Cellular Localization	Secreted
Form	Liquid
Concentration	0.5 mg/mL
Conjugation	Biotin
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration Date	12 months
Shipping	Ice bag

Cat.No.	Product Name	Sizes
E-CK-A091	Cell Stimulation and Protein Transport Inhibitor Kit	500Assays , 200Assays , 100Assays , 50Assays
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL
E-CK-A109	Intracellular Fixation/Permeabilization Buffer Kit	500Assays , 100Assays , 50Assays

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17F3

BL168

TC11-18H10.1

Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1] (E-AB-F1199B)