bcl-6 Monoclonal Antibody (PA7110)
For research use only.
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | bcl-6 |
| Cellular Localization | nucleus |
| Tissue Specificity | Tonsil |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
| background | BCL-6 is a proto-oncogene encoding the 95kDa Kruppel type zinc finger protein, which is homologous to other transcription factors. BCL-6 is expressed in normal follicular germinal center B cells and other associated lymphomas. BCL-6 expression can be detected in follicular lymphoma, diffuse large B-cell lymphoma, Burkitt lymphoma, and nodular lymphocyte-dominated Hodgkin's lymphoma. Positive expression of BCL-6 can be detected when splenic marginal band lymphomas transform into diffuse large B-cell lymphomas, and positive expression can also be detected in vascular immunoblastic T-cell lymphomas. In addition, it should be noted that many normal T cells also express BCL-6. |
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