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For research use only.

Verified Samples Verified Samples in IF: PC3
Verified Samples in FCM: PC-3
Dilution ICC/IF 1:50-1:1000,  FCM 1:25-1:100,  
Isotype IgG2b
Host Mouse
Reactivity Human
Applications FCM,  ICC/IF
Clonality Monoclonal
Immunogen Recombinant Human B7-H3 / CD276 protein
Abbre CD276
Synonyms B7H,  UNQ,  PRO,  B7-H,  B7RP,  B7 homolog,  B7H34Ig-B7-H,  PSEC,  4Ig-B7-H,  CD276,  4Ig-B7-H3,  B7-H3,  B7H3,  B7RP-2,  B7 homolog 3,  B7H34Ig-B7-H3,  CD276 antigen,  CD276 molecule,  Costimulatory molecule,  PSEC0249,  UNQ309,  PRO352,  B7RP-2,  4Ig-B7-H3,  B7H3,  B7-H3,  CD276 antigen
Swissprot
Cellular Localization Membrane
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Immunology,  Cancer,  Stem Cells
Clone No. 1F13
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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