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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human thyroid cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human ATXN7L3
Abbre ATXN7L3
Synonyms AT7L3,  Ataxin 7 like 3,  Ataxin 7 like protein 3,  Ataxin-7-like protein 3,  SAGA associated factor 11 homolog,  SAGA-associated factor 11 homolog,  atxn7l3
Swissprot
Cellular Localization Nucleus.
Concentration 1.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cell Biology,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
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Unconjugated

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