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For research use only.

Verified Samples Verified Samples in WB: NIH/3T3, A172
Verified Samples in IHC: Human thyroid cancer, Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
ClonalityPolyclonal
ImmunogenRecombinant protein of human ATG5
AbbreATG5
SynonymsAPG 5,  APG 5L,  APG5,  APG5 autophagy 5 like,  APG5 like,  APG5-like,  APG5L,  ASP,  ATG 5,  ATG5,  ATG5 autophagy related 5 homolog,  Apoptosis specific protein,  Apoptosis-specific protein,  Atg5,  Autophagy protein 5,  Autophagy related 5,  Homolog of S Cerevisiae autophagy 5,  hAPG5
Swissprot
Calculated MW32 kDa
Cellular LocalizationCytoplasm. Preautophagosomal structure membrane. Colocalizes with nonmuscle actin. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Concentration0.4 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Cell Biology,  Cardiovascular,  Metabolism,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundAutophagy protein 5 is a protein that in humans is encoded by the ATG5 gene.It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation.It is activated by ATG7 and forms a complex with ATG12 and ATG16L1.This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated