ASNA1 Polyclonal Antibody (E-AB-53162)

For research use only.
Verified Samples |
Verified Samples in IHC: Human thyroid cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ASNA1 |
Abbre | ASNA1 |
Synonyms | 1, ARSA, ARSA 1, ARSA I, ARSA-I, ARSA1, ARSAI, ATP binding, ATP-binding, ArsA arsenite transporter, ArsA arsenite transporter ATP binding homolog 1, Arsenical pump driving ATPase, Arsenical pump-drivi, E. coli, homolog 1 (bacterial), homolog of |
Swissprot | |
Cellular Localization | Cytoplasm. Endoplasmic reticulum. Nucleus>nucleolus. |
Concentration | 1.26 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway. |
Other Clones
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Other Formats
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Unconjugated
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